Aqui você encontrará apresentações realizadas nas Conferências de Usuários COMSOL de todo o mundo. As apresentações englobam pesquisas e produtos inovadores feitas por engenheiros e cientistas usando o COMSOL Multiphysics. Os tópicos abramgem uma grande gama de indústrias e aplicações, como elétrica, mecânica, escoamento e química. Use a função de busca "Quick Search" para encontrar apresentações na sua área de interesse.

Modelling of the Oxygen Consumption of Cells in the Cell Culturing Platform - new

A. Niazi[1]
[1]School of Mechanical Engineering, University of Birmingham, Birmingham, United Kingdom

A device for monitoring the oxygen consumption of cells has been developed, which consists of two parts; a cell culturing platform (CCP) and an oxygen sensing chip. The CCP possesses inlet and outlet pipes to direct the fluid under the test to the cell culturing chamber through the inlet pipe and goes out of the outlet pipe after being partially consumed by the cells. In this abstract, the ...

3-D Finite Element Modeling of Brain Edema: Initial Studies on Intracranial Pressure Using COMSOL Multiphysics®

X.G. Li[1], H. von Holst[1][2], J. Ho[1], and S. Kleiven[1]

[1]Division of Neuronic Engineering, KTH, Stockholm, Sweden
[2]Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden

Brain edema is one of the most common consequences of serious traumatic brain injuries which is usually accompanied with increased Intracranial Pressure (ICP) due to water content increment. A three dimensional finite element model of brain edema is used to study intracranial pressure in this paper. Three different boundary conditions at the end of Cerebral Spinal Fluid (CSF) were used to ...

Virtual Thermal Ablation in the Head and Neck using COMSOL Multiphysics

U. Topaloglu[1], Y. Yan[2], P. Novak[2], P. Spring[3], J. Suen[3], and G. Shafirstein[3]
[1] Department of Information Technology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
[2]Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
[3]Department of Otolaryngology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

Thermal ablation in the head and neck requires accurate thermal dose delivery to target tissue while protecting the structure and function of nearby tissue and organs. In this study, we present a method that allows importing Computed Tomography (CT) scans to COMSOL, in order to model accurately the expected pathological outcomes prior to thermal ablation treatment. Thermal ablation of a virtual ...

Dynamic Simulation of Bone Morphogenetic Protein Patterning in a 3D Finite-Element Model of the Danio Rerio Embryo

D. Umulis, and S. Lee
Purdue University
West Lafayette, IN

Zebrafish development of the dorsoventral axis relies on the spatiotemporal distribution of Bone Morphogenetic Protein (BMP) signaling, which is regulated by numerous secreted molecules such as Tolloid, Sizzled, and Chordin. The rich dorsal/ventral patterning network must achieve both spatial precision in the patterning of downstream targets and confernspatial precision at distinct time points ...

A Multiphysics Approach to the Modeling of Biological Prosthetic Heart Valves

A. Avanzini[1], D. Battini[1], M. Berardi[1]
[1]Università degli Studi di Brescia, Brescia, Italy

The complex behavior of biological prosthetic heart valves was simulated. A multiphysics computational approach was adopted using different modules of COMSOL Multiphysics: the LiveLink(TM) interface was used to exchange the valve geometry with CAD, Structural Mechanics Module to set loads, boundary conditions and implement anisotropic hyper-elastic constitutive laws for leaflet tissue, PDE to ...

A Model of Noninvasive Radiofrequency Tissue Heating

L. Rems[1], D. Miklavcic[1]
[1]University of Ljubljana, Faculty of Electrical Engineering, Ljubljana, Slovenia

Noninvasive radiofrequency (RF) tissue heating is frequently used for skin tightening and facial wrinkle reduction as alternative to invasive surgical procedures. However, to ensure a safe and efficient therapy, the temperature of the skin and the subcutaneous tissue must be controlled in order to prevent tissue damage. We used numerical modeling to investigate the dynamics of the temperature ...

Numerical Simulations Demonstrate Safe Vitrification and Warming of Embryos Using the Rapid-i™ Device

B.O.J. Johansson[1][2], Y.A. Tarakanov[1], H.J. Lehmann[2], and S.P. Apell[1]

[1]Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden
[2]Vitrolife Sweden AB, Västra Frölunda, Sweden

During cryopreservation of human embryos, ice crystal formation in the embryos or in surrounding media may cause cryodamage to them and can be lethal. A strategy to avoid this is the vitrification procedure when the embryo and the surrounding medium undergo the transition to glassy state rather than a crystalline one during cooling. Similarly, recrystallization in the embryo or the medium must ...

Transport of Vocs through Bioflim in Biotrickling Filters

Balasubramanian P[1]
[1]Indian Institute of Technology Madras, Chennai, Tamil Nadu, India

Realising the interlinkage of nature and engineering are of paramount essential while comprehending the basics of system’s performances. Application of biotechniques in air pollution control is one such emerging scientific area, where the understandings of these complex systems demand more utilisation of computing softwares. Recently, biofiltration is a versatile biological air pollution control ...

On the Influence of Cancellous Bone Structure upon the Electric Field Distribution of Electrostimulative Implants - new

U. Zimmermann[1], R.Bader[2], U. van Rienen[1]
[1]Institute of General Electrical Engineering, University of Rostock, Rostock, Germany
[2]Department of Orthopaedics, University Medicine Rostock, Rostock, Germany

Since the 1980s, the accelerating effect of electromagnetic fields on bone regeneration is used to treat complicated fractures and bone diseases. At the University of Rostock, an electrostimulative hip revision system is developed, basing on the method of Kraus-Lechner. This method requires an electric fields between 5 and 70 V/m. The bone used for the simulations consisted of two homogenous ...

A Virtual Pharmacokinetic Model Of A Human Eye

L. Murtomäki, and S. Kotha
University of Helsinki, Centre for Drug Research, Helsinki, Finland

Drug therapy of the posterior part of an eye is very challenging. Yet, in USA alone, there are almost 2 million people affected by age related macular degeneration. When designing a strategy for controlled-release drug delivery, it is important to take into account of physiology, absorption, distribution, metabolism, and excretion properties of a drug. Therefore, the aims of this study are: 1) ...