Aqui você encontrará apresentações realizadas nas Conferências de Usuários COMSOL de todo o mundo. As apresentações englobam pesquisas e produtos inovadores feitas por engenheiros e cientistas usando o COMSOL Multiphysics. Os tópicos abrangem uma grande gama de indústrias e aplicações, como elétrica, mecânica, escoamento e química. Use a função de busca "Quick Search" para encontrar apresentações na sua área de interesse.

Computationally Assisted Design and Experimental Validation of a Novel ‘Flow-Focussed’ Microfluidics Chip for Generating Monodisperse Microbubbles

M. Conneely[1], V. Hegde[2], H. Rolfsnes[1], A. Mason[2], D. McLean[1], C. Main[1], F.J.D. Smith[2], W.H.I. McLean[2], P.A. Campbell[1]
[1]Carnegie Physics Laboratory, University of Dundee, Dundee, Scotland, United Kingdom
[2]Division of Molecular Medicine, University of Dundee, Dundee, Scotland, United Kingdom

Whilst initially developed as a diagnostic aid to improve echogenicity in ultrasound imaging, gas-filled lipid microbubbles are now emerging as a next generation \'theranostic\' tool in the medical arena. Here, their therapeutic potential has now been realized through their unique capability to deliver molecular species such as drugs and genes by means of disrupting the cell membrane in response ...

An Assessment of the Suitability of the Body and Adult Head Coils for Transmission during Paediatric Magnetic Resonance Imaging

G.R. Cook[1], M.J. Graves[1], F.J. Robb[2], D.J. Lomas[1]
[1]Department of Radiology, University of Cambridge, Cambridge, United Kingdom
[2]General Electric Healthcare Coils, Aurora, Ohio, USA

MRI offers many advantages over other modalities and its lack of ionizing radiation is important for children, but can be limited by the radio-frequency (RF) coils available. This work calculates Specific Absorption Rate (SAR) and homogeneity of the RF transmit field (B1+) when imaging infants in adult coils. Two birdcage-type coils were loaded by a tissue model and their B1+ homogeneities ...

Analysis to Determine Optimum Strain Gauge Locations for SENSEWHEEL - new

T. Suzuki[1], C. Holloway[1], S. Taylor[1]
[1]University College London, London, UK

Manual wheelchair users suffer shoulder pain and injury in the long term because of unconscious overuse. The ‘SENSEWHEEL’, which interposes three identical load cells between pushrim and rear wheel, measures the three components of pushing force Fx, Fy and Fz, and axial torque Tx applied at each load cell. Strain gauges were located on a diaphragm forming one face of the load cell. The ...

Design and Strain Analysis of Artificial Femoral Head and Stem

N. M. Sundaram[1], M. Sneha[1], A. Kandaswamy[1], R. Nithya[2]
[1]PSG College of Technology, Coimbatore, Tamil Nadu, India
[2]Dr. N.G.P. Institute of Technology, Coimbatore, Tamil Nadu, India

The majority of elderly patients are subjected to hip bone replacement due to dislocation of bone, mechanical failure and infection. The life time of the implant varies from patient to patient depending on their daily physical activity. Once the implant fails, re-operation of hip bone replacement is performed. In United States, there are approximately 18 revision hip replacements performed for ...

Advancing Regulatory Science through Integrative Engineering with COMSOL Multiphysics® Software Modeling

G. Zhang [1]
[1] Department of Bioengineering, Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA

The US Food and Drug Administration (FDA) faces significant challenges in its regulatory approval processes due to a lack of relevant science, and many practices are limited by laws enacted in the previous century [1]. Therefore, in recent years, the FDA has identified the need for advancements in regulatory science and innovation. In a broader sense, advancing regulatory science is not just ...

Numerical Simulations Demonstrate Safe Vitrification and Warming of Embryos Using the Rapid-i™ Device

B.O.J. Johansson[1][2], Y.A. Tarakanov[1], H.J. Lehmann[2], and S.P. Apell[1]

[1]Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden
[2]Vitrolife Sweden AB, Västra Frölunda, Sweden

During cryopreservation of human embryos, ice crystal formation in the embryos or in surrounding media may cause cryodamage to them and can be lethal. A strategy to avoid this is the vitrification procedure when the embryo and the surrounding medium undergo the transition to glassy state rather than a crystalline one during cooling. Similarly, recrystallization in the embryo or the medium must ...

Analysis of Heat Transfer in a Complex Three Dimensional Structure Fabricated by Additive Manufacturing - new

C. Settle[1], K. Hoshino[1]
[1]Biomedical Engineering Department, University of Connecticut, Storrs, CT, USA

The goal of this study was to create a three dimensionally designed biomedical device with multiple functionalities and analyze its simulated heat transfer. The device would be fabricated through additive manufacturing; specifically electron beam melting (EBM). EBM has a feature size constraint of 1 mm (acceptable for this design) and is only capable of manufacturing titanium alloys [2]; a ...

Computational Design and Optimization of Bone Tissue Engineering Scaffold Topology

N. P. Uth [1], J. Mueller [2], B. Smucker [3], A. Yousefi [1],
[1] Department of Chemical, Paper, and Biomedical Engineering, Miami University, Oxford, OH, USA
[2] Research Computing Support, Miami University, Oxford, OH, USA
[3] Department of Statistics, Miami University, Oxford, OH, USA

Introduction: Bone tissue has a limited ability for regeneration; critically sized defects cannot self-heal and require medical intervention. Bone tissue engineering (TE) circumvents this issue by growing replacement bone tissue from the patient’s own cells inside scaffolds. TE scaffolds are porous constructs that act as a support structure during bone regeneration and helps cells attach and ...

Simulating Corrosion in a Crevice of Commercial Pure Titanium

G. Zhang [1, 2, 3],
[1] Department of Bioengineering, Clemson University, Clemson, SC, USA
[2] Department of Electrical and Computer Engineering, Clemson, SC, USA
[3] Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA

Implant devices are assistive devices surgically placed in the human body to restore the functionality of organs and tissues. Metallic implants are often used for load bearing applications including the hip and knee joints. To allow maximum flexibility during surgery for surgeons to pick and choose different combinations of parts (say, head, neck and stem, in the case of total hip replacement), ...

Muscle-Electrode Interface Simulation

A. Altamirano, C. Toledo, A. Vera, R. Muñoz, and L. Leija
Centro de Investigacion y Estudios Avanzados
Instituto Politecnico Nacional
Mexico

In this article, the aim is to study different types and forms of electromyography (EMG) electrodes, for bipolar configuration, and the electric interface with muscle phantom. COMSOL Multiphysics allows modeling shapes and contact surfaces. Surface and needle electrodes will be modeled. A number of different trials and combinations will be presented; exploring different geometric shapes and ...